Friday, 12 April 2013
Monday, 8 April 2013
The contribution of Marie Skłodowska-Curie to the development of modern oncology
A great read: The contribution of Marie Skłodowska-Curie to the development of modern oncology http://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3093546/
"At the end of 19th century a few fundamental discoveries changed
diagnostic and therapeutic possibilities in medicine and, particularly,
in oncology: in 1895 Wilhelm Roentgen from Germany discovered X-rays, in
1886 Henry Becquerel described the phenomenon of radioactivity of
uranium, and in 1898 Marie and Pierre Curie discovered radium and
polonium. In 1903 the Nobel Prize for Physics was awarded jointly to
Henry Becquerel, and Marie and Pierre Curie for the discovery of
radioactivity. Maria Skłodowska-Curie received the 1911 Nobel Prize for
Chemistry for her discovery of radium and polonium"
"A relatively new technique based on the discoveries of Marie Skłodowska-Curie is nuclear medicine which uses substances labeled with radioisotopes introduced into the organs of the patient for imaging of the tumors. Progress in nuclear medicine was possible after the Second World War when, after the discoveries of Frederic and Irene Joliot-Curie from 1930s, it became possible to produce artificial radioisotopes in amounts suitable for use in medicine"
Sunday, 7 April 2013
Short-term, applied research won't win Canada any Nobel prizes by David Naylor, President of the University of Toronto
A
good read: Short-term, applied research won't win Canada any Nobel
prizes by David Naylor, President of the University of Toronto: http:// www.theglobeandmail.com/news/ national/education/ short-term-applied-research-won t-win-canada-any-nobel-prizes/ article10367360/ ?utmsource=enews
"There’s a popular myth about universities as ivory towers full of
fat-cat academics and loopy students asking unanswerable questions.
Their willful irrelevance is a waste of taxpayers’ money, so the critics
say; get them out of the public trough and doing things Canadian
business can really use. I call it a Zombie idea. It’s dangerous,
because it has infected some decision-makers. And it’s hard to kill,
because there is some truth, and therefore some life in it.
On this
latter point, recall that federal and provincial governments sharply
increased their spending on research starting in the 1990s. We owe a
debt to the university leaders who advocated for those increases. But,
in making the case, they expected an economic bonanza – just a hop and a
skip from the lab bench to new multinational superstar companies.
Everyone forgot that the private sector – not universities – ultimately
drives commercialization. Failure to meet those expectations has helped
feed the research Zombie, increasing the clamour for applied research
with a short-term orientation.
In fact this Zombie has already had
an effect on research funding. The data in the first accompanying graph,
Fettered and Unfettered Research, show the funding patterns for the
Natural Sciences and Engineering Research Council of Canada over the
last 30 years.
You can see the pronounced trend. Converting the
proportions into real dollars, about $230-million of federal funding has
moved from unfettered to fettered research at the University of Toronto
over the past five years alone, roughly consistent with a pattern
stretching back almost a generation. In other words, we are already
engaged with partners. We are already engaged in match-funded,
industry-facing research with an applied orientation. This is a national
trend, driven by funding decisions over many years.
But did anyone
notice that our innovation and competitiveness indicators improved over
this period? I didn’t. In fact, the real problem was never the type of
research that universities were doing – we had the wrong diagnosis, and
the wrong prescription. It was business-related R&D spending that
lagged, which is why the Jenkins Panel (on which I was privileged to
serve) was convened by the Minister of State for Science and Technology,
to examine how to stimulate business spending on innovation.
This
funding ecosystem, combined with many disincentives to excellence, makes
it harder for us to reach the top tier of the podium. Perhaps this is
why Canada has had no home-grown Nobel laureates for 20 years. The
research Zombie masters would have you believe that it doesn’t matter.
Nobel, Schnobel – let’s level down in the best Canadian tradition and go
for the bronze. But there are very good reasons why great basic,
disruptive, fundamental research matters.
The first is that the
success of home-grown Nobel laureates – not imports – raises aspirations
for everyone. Their scholarship inspires and attracts others to follow.
Put another way, a country where world-shaking discoveries are made
routinely is a country that will always be able to compete by attracting
the best and brightest to its shores.
The second is that great
scholars doing fundamental research are often inspiring teachers. Ray
Jawardhana, for example, is a star-gazer, hunting for Earth-like
planets. What’s the value of that? You can’t turn that into a product or
service tomorrow. But Professor Jawardhana’s work raises fundamental
questions about humanity’s place in the cosmos. He and countless other
colleagues spend their lives asking questions that stretch young minds
and change expectations. We want – and we need – a generation of young
Canadians for whom the sky itself is not the limit.
And here is a
third reason why serious fundamental research matters. In my field,
medical research, countless discoveries with no immediate application
turned out to be the foundations for life-changing and live-saving
innovations in clinical care. You can’t predict this in advance. We need
to remember that the distinction between fundamental and applied
research is misleading. As Nobel laureate Sir George Porter famously
pointed out, there is applied research and yet-to-be-applied research.
Geoffrey Hinton’s research into machine learning algorithms and deep
neural networks is a brilliant case in point. It has led to unexpected
advances in computer vision, speech-recognition, data mining, and –
astonishingly – real-time language translation that is now used by
Google and Microsoft.
There is another facet here. One needs
excellence in research and scholarship across disciplines because no one
can predict how disciplines will collide. So much of the best
innovation is convergent.
Here is just one fascinating example.
Lorna MacDonald teaches performance, opera, and vocal pedagogy in U of
T’s Faculty of Music – a very strong program, internationally renowned.
At the same time, Professor MacDonald collaborates with the clinicians
at the Hospital for Sick Children on cochlear implants, laryngology,
speech-language pathology, and pediatric voice and hearing care.
In
closing, I offer both a warning and a note of optimism. First, the
warning. The second graphic, Measuring Up in Global Rankings, presents
composites of rankings across multiple league tables involving Canada’s
research-intensive universities.
The data suggest that not enough of
our best research universities are figuring strongly on the world
stage. And some of them are at serious risk of losing ground. In one
jurisdiction after another – China, Brazil, Singapore, France, Germany,
the U.S. and the U.K. – major targeted investments have been made to
ensure that the strongest research universities are able to compete
globally.
Earlier this month, the Times Higher Education group
released their rankings of university reputations. These results are
based on a survey of thousands of professors worldwide. McGill and the
University of British Columbia went from 31st from 25th place. Toronto
held steady at 16th. (The third graphic, Canadian Universities in World
Rankings, shows these comparative rankings)
Let me share the warning
from Phil Baty, the editor of the Times Higher Education rankings and a
veteran observer of universities worldwide. Mr. Baty said that the
decline was a direct result of Canada’s “highly egalitarian approach.”
He put it precisely: “Countries around the world are picking winners and
investing heavily in them, so they are coming up the ranks while Canada
is slipping.”
Sobering as it is, Mr. Baty’s concise formulation
does not address what for me is the most important asset of all – and
the asset that will be devalued the most if the Zombies win. I am
referring, of course, to young talent. The resources that matter most
aren’t in the ground or offshore. The resources that will win the day
for Canada are the inquiring, agile, and creative minds of the next
generation.
I continue to believe that, given the right education
and opportunities, with a full suite of institutions with different
missions, including research universities that can compete on the global
stage, the next generation of Canadians will make great discoveries,
develop transformative technologies, imagine more successful societies,
ask hard questions, and lead with verve and vision. I also have faith
that, in the years ahead, if we make the right choices, the Zombies will
disappear – and our young people will secure a bright future for this
great country.
David Naylor is the president of the University of
Toronto. This article is abridged from a speech to the Empire Club
earlier this month."
Friday, 5 April 2013
The Tar Sands Disaster
A must read: The Tar Sands Disaster: http://www.nytimes.com/2013/ 04/01/opinion/ the-tar-sands-disaster.html?src =rechp&_r=1&
" Both the cabinet and the Conservative parliamentary caucus are
heavily populated by politicians who deny mainstream climate science.
The Conservatives have slashed financing for climate science, closed
facilities that do research on climate change, told federal government
climate scientists not to speak publicly about their work without
approval and tried, unsuccessfully, to portray the tar sands industry as
environmentally benign.
The federal minister of natural resources,
Joe Oliver, has attacked “environmental and other radical groups”
working to stop tar sands exports. He has focused particular ire on
groups getting money from outside Canada, implying that they’re acting
as a fifth column for left-wing foreign interests. At a time of
widespread federal budget cuts, the Conservatives have given Canada’s
tax agency extra resources to audit registered charities. It’s widely
assumed that environmental groups opposing the tar sands are a main
target.
This coercive climate prevents Canadians from having an open
conversation about the tar sands. Instead, our nation behaves like a
gambler deep in the hole, repeatedly doubling down on our commitment to
the industry. "
Thursday, 4 April 2013
Can household solar photovoltaics provide a primary source of low-emission power?
Can household solar photovoltaics provide a primary source of low-emission power? http://bravenewclimate.com/ 2013/04/01/ household-pv-primary-le-power/ #more-6096
"PV’s greatest strength lies in being embedded within the low voltage
distribution network as a supplementary power source, where it can
potentially provide valuable network support, but will require
electricity market reform along with a substantial decline in lifetime
battery costs. The conclusion is that the short-run tactical response of
the expansion of PV without storage works against a long-run strategic
approach to deep emission cuts, which will ultimately require the
successful adoption of one or more of the candidate low-emission
baseload technologies."
How do Russia and the US measure up on SMRs?
How do Russia and the US measure up on SMRs? http:// analysis.nuclearenergyinsider.c om/small-modular-reactors/ how-do-russia-and-us-measure-sm rs?utm_source=http%3A%2F%2Fuk. nuclearenergyinsider.com%2Ffc_ nei_decomlz%2F&utm_medium=emai l&utm_campaign=NEI+e-brief+020 4&utm_term=How+do+Russia+and+t he+US+measure+up+on+SMRs&utm_c ontent=151899
"Recent developments have focused attention on small modular reactor
activity in the US. But Russia is pressing ahead with developments of
its own.
As previously reported in Nuclear Energy Insider, the
mPower America Team, made up of the Babcock & Wilcox Company, the
Tennessee Valley Authority and Bechtel, is powering ahead with SMR
commercialisation plans after winning US Department of Energy funding.
Meanwhile other American SMR developers, including Westinghouse,
NuScale Power, Gen4 Energy and SMR LLC, are pressing forward with
ambitious programmes of their own.
At stake, not only an important
domestic market, but also the potential for exports to emerging nuclear
customers in regions such as the Middle East and North Africa. But US
manufacturers are not alone in the race to make SMRs a commercial
reality."
Rocket powered by nuclear fusion could send humans to Mars
Tuesday, 2 April 2013
AECL CEO Doctor Bob Walker talks about possibility of a new research reactor at Chalk River
AECL
CEO Doctor Bob Walker talks about possibility of a new research reactor
at Chalk River: Considering that it takes about 10 years to design and
build a new research reactor and several more years to build and
commission neutron scattering instruments, even if such a future
research reactor included neutron beams, it may be too late to avoid a
neutron gap and maintain the existing neutron scattering competency in
Canada... http://www.renfrewtoday.ca/ default.asp?pid=476487&wireid=0 1195_ARP_AECLupdate1_052316:
"A new reactor is a possibility for Chalk River. AECL is gearing up for
the second phase of restructuring, and AECL CEO Doctor Bob Walker
presented County Council with an overview of the plans over the next
four years. One of the possibilities is a government - commercial
partnership to build a new research reactor sometime after 2016. He says
the government is not willing to go it alone but would be willing to
talk about cost sharing.
These changes will not come overnight.
It is expected selecting a new consortium to take over management of the
lab will take two years, followed by a phase in period of an additional
two years. AECL currently contributes $300 million in salaries and an
additional $250 million in supplies and services to the Renfrew County
economy."
OPAL Research Reactor
A great short video on OPAL Research Reactor: http://www.ansto.gov.au/ AboutANSTO/OPAL/index.htm
"Australia’s Open Pool Australian Lightwater (OPAL) reactor is a
state-of-the-art 20 Megawatt reactor that uses low enriched uranium
(LEU) fuel to achieve a range of nuclear medicine, research, scientific,
industrial and production goals."
Report predicts $5.5B radiopharma market by 2017
Report predicts $5.5B radiopharma market by 2017: http://www.auntminnie.com/ index.aspx?sec=ser&sub=def&pag= dis&ItemID=102995
"The report estimates that Tc-99m diagnostic procedures are expected to
increase by more than 15% in mature markets of North America, Europe,
Japan, South Korea, and Asia-Pacific nations between 2010 and 2030.
However, a shortage of molybdenum-99, the precursor to Tc-99m, has been a
threat to this industry. Also, the high cost of devices using
radioisotopes, short half-lives, lack of good manufacturing practices,
and stringent regulatory approvals are major hurdles to growth of the
market, according to the report.
The scheduled shutdowns of the
National Research Universal (NRU) reactor in Canada in 2016 and the
Osiris reactor in France in 2018 pose major risks for manufacturers in
the near future, MarketsandMarkets noted. However, radiopharmaceutical
companies have increased the production of thallium to meet the
shortage, as it is the radiopharmaceutical most commonly used as a
substitute for technetium-99 in cardiac stress tests."
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